Trenbolone is without a doubt the most powerful injectable anabolic steroid used by Steroid.com members to gain muscle mass. However, the full properties of the drug are not always fully understood. This profile separates fact from fiction to help Steroid.com members decide if Trenbolone is right for them.

Trenbolone is similar to the very popular steroid Nandrolone in that they are both 19-nor steroids meaning that the testosterone molecule at position 19 has been altered to give us a new compound. However, unlike nandrolone, trenbolone is an excellent mass gainer and muscle builder, much of which comes from muscle fibers with minimal water retention (1). It has an incredible anabolic (muscle building) score of 500. When you compare this to Testosterone, itself a powerful mass builder, and its anabolic score of 100, you can begin to understand Trenbolone’s muscle building potential. What Makes Trenbolone So Anabolic? Many factors play a role. Trenbolone significantly increases levels of the extremely anabolic hormone IGF-1 in muscle tissue (2). And it’s worth noting that not only does it more than double muscle IGF-1 levels, but it also makes muscle satellite cells (the cells that repair damaged muscles) more sensitive to IGF-1 and other growth factors (3). The amount of DNA per muscle cell can also be significantly increased (3).

Trenbolone also has a very strong androgen receptor (AR) binding affinity, binding much more strongly than testosterone (4). This is important because the stronger the steroid binds to the androgen receptor, the better the steroid will work to activate AR-dependent muscle growth mechanisms. There is also strong evidence that compounds that bind very strongly to the androgen receptor also promote fat loss. Think of receptors as locks and androgens as different keys, with some keys (androgens) opening (binding) locks (receptors) much better than others. This does not mean that AR binding is the last word in terms of steroid effectiveness. Anadrol has no measurable association with AR and we all know how effective Anadrol is for bulking.

Trenbolone increases nitrogen retention in muscle tissue (5). This is important as nitrogen retention is a strong indicator of how anabolic a substance is. The incredible mass-building effects don’t stop there, however. Trenbolone has the ability to bind to anti-anabolic (muscle damaging) glucocorticoid hormone receptors (6). It may also have the effect of inhibiting the catabolic (muscle-damaging) hormone cortisol (7).

Another surprising trait is its ability to improve feed efficiency and mineral intake in treated animals (8). To help you understand what this means for you, feed efficiency is a measure of how much of an animal’s food is converted into meat, and the more feed it takes to produce that meat, the lower the efficiency. Conversely, the less food is needed for meat production, the higher the efficiency and you get the idea. Animals treated with trenbolone gained quality weight without dietary changes, which increased feed efficiency. The search for new compounds that can improve feed performance is a multi-billion dollar industry that has led to many nutritional advances in the bodybuilding world over the last several decades (CLA, whey protein and HMB are the compounds that come to mind) . occurred in animal husbandry). What does this mean for a hard training athlete? The food consumed is better utilized for muscle building and vitamins and minerals are also better absorbed, which can support your cycle health.

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Trenbolone is also a highly androgenic hormone compared to testosterone which has an androgenic ratio of 100; Trenbolone’s androgenic ratio is a staggering 500. Highly androgenic steroids are valued for their effects on strength as well as altering the estrogen/androgen ratio, which also reduces the amount of water under the skin. As if the Trenbolone review isn’t good enough, it just keeps getting better; Trenbolone is extremely good for weight loss. One reason for this is its powerful effect on nutrient distribution (9). A little-known fact is that androgen receptors are found in both fat cells and muscle cells (10), androgens act directly on the AR in fat cells and affect fat burning. (11) The stronger the androgens bind to the AR, the greater the lipolytic (fat burning) effect on adipose tissue (fat) (11). There aWhile some steroids actually increase the amount of AR in muscle and fatx (11, 12) this fat loss effect can be enhanced by the concomitant use of other compounds such as testosterone.

Trenbolone boosts red blood cell production and increases the rate of glycogen replenishment, greatly improving recovery (13). Like almost all steroids, its effects are dose dependent, with higher dosages having the greatest impact on body composition and strength. Mental changes are a notorious side effect of trenbolone (15), androgens increase brain chemicals that promote aggressive behavior (16), which may be beneficial for some athletes looking to improve speed and strength.

Chemical structure of trenbolone

The chemical structure of trenbolone makes it resistant to aromatizing enzymes (conversion to estrogen), so absolutely no percentage of trenbolone is converted to estrogen. Trenbolone intake does not contribute to the development of estrogenic side effects, such as B. Growth of breast tissue in men (gynecomastia, female breasts), accelerated fat gain, reduced fat loss and water retention. Trenbolone is also resistant to the 5-alpha-reductase enzyme, an enzyme that reduces some steroid hormones into a more androgenic form, but that doesn’t matter in this case. Trenbolone has an androgenic ratio of 500. It can easily cause adverse androgenic side effects in people prone to hair loss, prostate enlargement, oily skin and acne. Unfortunately, the possible negative side effects of Trenbolone don’t stop there. Trenbolone is also an outstanding progestin: it binds to the progesterone receptor of the female sex hormone (with about 60% of the actual potency of progesterone) (17). Worse, trenbolone’s active metabolite, 17beta-trenbolone, has a binding affinity for the progesterone receptor (PgR) that is actually greater than progesterone itself (18). But don’t panic, the anti-estrogen letrzole or fulvestrant can lower your progesterone levels and fight progesteral side effects. Using a 19-nor compound like trenbolone also increases prolactin &. Bromocriptine or cabergoline are often recommended to lower prolatin levels (20). Testicular atrophy (shrunken eggs) can also occur; HCG used intermittently throughout the cycle can prevent this. (21) It is also advisable for Tren users to closely monitor cholesterol levels as well as kidney function and liver enzymes as Tren can negatively affect all of these functions. Finaplix, a powerful progestin, also suppresses natural testosterone production, which, even at relatively low doses, keeps testosterone levels low for long periods of time, which can reduce libido and cause erectile dysfunction (fina dick).

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The acetate ester is a very short chain ester attached to the Finaplix molecule. It has an active lifespan of 2-3 days, but daily injections are often recommended to maintain high and stable blood levels of Trenbolone. The acetate ester offers fast and high concentration of the hormone, which is beneficial for those looking for rapid development, combined with the acetate ester’s fast elimination time, which can be discontinued if adverse side effects are experienced.

Now that Trenbolone Acetate’s properties have been explained, we can better understand how to use it to maximize its benefits. Evidence suggests that finaplix combined with estrogen promotes more weight gain than trenbolone alone (22), now I’m not telling you to use birth control with your tren, but I’m adding aromatizing oral drugs like Dianabol and long-term compound testosterone. for example Cypionate or Enanthate will give great results in a mass gain cycle. Finaplix is ​​the best choice for cutting cycles; Trenbolone’s powerful effect on nutrient transfer allows the user to cut calories and stay in a state of positive nitrogen balance (remember what that means?). The cortisol lowering effects and binding to the glucocorticoid receptor will greatly reduce the catabolic effects of rigid dieting and excessive amounts of cardio, not to mention that Finaplix itself can burn fat (due to its strong AR binding). Winstrol can be used along with Tren in a cutting cycle. Winstrol has low AR binding affinity and therefore works in your body in a completely different way than Tren (i.e. no receptor-mediated effect). Also, Winstrol is a DHT based drug and Tren is 19-nor, adds some testosterone (supportng) and you will have a slicing cycle that uses all 3 major anabolic steroid families (testosterone, 19-nor). , and DHT), as well as completely different affineAR binding sites and mechanisms of action. in action that is not mediated by receptors). Also, Winstrol is a DHT based drug and Tren is 19-nor, adds some Testosterone (support) and you will have a slicing cycle that uses all 3 major anabolic steroid families (Testosterone, 19-nor). and DHT) as well as very different AR binding affinities and mechanisms of action. in action that is not mediated by receptors). Also, Winstrol is a DHT based drug and Tren is 19-nor, adds some Testosterone (support) and you will have a cutting cycle that uses all 3 major anabolic steroid families (Testosterone, 19-nor). and DHT) and also differ greatly in AR binding affinities and mechanisms of action.

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Side effect

Side effect

Ironically, while Trenbolone (Tren) is a great pre-contest drug, it lowers thyroid levels (23), which increases prolactin levels. I recommend taking T3 (25 mcg/day) with Tren so you don’t over-inflate your prolactin levels this way.

In addition, this drug is a poor choice for athletes who rely on the cardiovascular system for sports. Trenbolone (Tren) decreases the ability of many athletes to maintain high levels of endurance, at least in some cases. Unfortunately, this makes Tren a poor choice for many.

Right now, the main source of Trenbolone is bovine implants, which are converted into injectable or transdermal compounds from powder and naturally from underground labs. “Home brew” powder or bovine implants seem to be the preferred method of obtaining injectable Trenbolone Acetate as the user has much more control over the drug’s potency and sterility. Trenbolone is much more expensive than other anabolic steroids, starting at $15 per gram of powder, or $150 for a single 10mL vial. The cost of Trenbolone doesn’t matter, it’s worth every penny.